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Department of Epidemiology and Public Health,
University of Navarre, Pamplona, Spain. mamartinez@unav.es
OBJECTIVE:
To assess the association between a first
acute myocardial infarction and the consumption
of fibre and fruit.
DESIGN: Hospital-based
case-control study with incident cases. A
validated semi-quantitative food frequency
questionnaire (136 items) was used to assess
food intake.
SETTING: Three third-level university
hospitals in Pamplona (Spain).
SUBJECTS:
Cases were subjects aged under 80, newly
diagnosed with acute myocardial infarction.
Each case patient (n=171) was matched to
a control subject of the same gender and
age (5 y bands) admitted to the same hospital.
RESULTS:
An inverse association was apparent for the
three upper quintiles of fibre intake. After
adjustment for non-dietary and dietary confounders,
an inverse linear trend was clearly significant,
showing the highest relative reduction of
risk (86%) for the fifth quintile (OR=0.14,
95% confidence interval: 0.03-0.67). An inverse
association was also apparent for fruit intake,
but not for vegetables or legumes.
CONCLUSIONS:
Our data suggest that a substantial part
of the postulated benefits of the Mediterranean
diet on coronary risk might be attributed
to a high intake of fibre and fruit.
PMID: 12122546 [PubMed - indexed for MEDLINE] |