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Center for Perinatal Studies, Swedish Medical
Center, Seattle, WA 98122, USA. ihunnaya.frederick@swedish.org
OBJECTIVE:
To explore the relation between preeclampsia
risk and maternal intake of dietary fiber,
potassium, magnesium and calcium. STUDY DESIGN:
We conducted a case-control study of 172
preeclamptics and 339 normotensive controls.
Maternal dietary intake was assessed using
a food frequency questionnaire. Logistic
regression procedures were used to estimate
the association between each dietary factor
and preeclampsia risk.
RESULTS: Fiber intake
was inversely associated with the risk of
preeclampsia. When extreme quartiles of total
fiber intake were compared, the odds ratio
(OR) for preeclampsia was 0.46 (95% confidence
interval [CI] 0.23-0.92). The multivariate
OR for preeclampsia for women in the top
quartile of potassium intake (> 4.1 g/d)
versus the lowest quartile (< 2.4 g/d)
was 0.49 (95% CI 0.24-0.99).
There was some
evidence ofa reduced risk of preeclampsia
with a high intake of magnesium and calcium,
though these results were not statistically
significant. Intake offruits and vegetables,
low-fat dairy products, total cereal and
dark bread were each associated with a reduced
risk of preeclampsia.
CONCLUSION:
Our results support previous reports
that suggest that diets high in fiber and
potassium are associated with a reduced risk
of hypertension. Maternal intake of recommended
amounts of foods rich in fiber, potassium
and other nutrients may reduce the risk of
preeclampsia. |